Endoret® (PRGF): Natural Skin Rejuvenation With Plasma Growth Factors

The Endoret® (PRGF) treatment is one of the most advanced procedures in regenerative aesthetic medicine. It uses your own purified plasma, enriched with powerful growth factors, to stimulate collagen production, improve the skin’s texture, and accelerate cell regeneration.

It is a safe, biocompatible, and 100% natural treatment, ideal for patients seeking visible improvements without invasive procedures.

Endoret® (PRGF) is a patented system that isolates the most active and beneficial plasma components responsible for tissue regeneration.

Compared to traditional PRP, Endoret® offers:

  • a higher concentration of growth factors,

  • greater biological stability,

  • more controlled release,

  • significantly less inflammation.

This is why Endoret® is considered one of the most effective plasma systems available.

Visible improvements:

  • Global facial rejuvenation

  • Reduction of fine lines and wrinkles

  • Brighter, more even skin tone

  • Reduction of mild pigmentation

  • Minimized pores

  • Increased firmness and elasticity

  • Revitalized and healthier-looking skin

Medical benefits:

  • Accelerates natural tissue repair

  • Stimulates fibroblasts to produce new collagen

  • Reduces redness and inflammation

  • Completely safe since it is autologous (your own plasma)

Endoret® is ideal for patients who want:

  • Natural, subtle rejuvenation

  • Improved texture, tone, and radiance

  • A treatment with no downtime

  • A boost in firmness and hydration

  • A complementary procedure to laser or IPL

Perfect for those looking for a fresh, youthful appearance without drastic changes.

  1. Blood extraction
    A small sample of blood is taken.

  2. Centrifugation and plasma isolation
    The Endoret® system separates the most potent growth factors.

  3. Application on the skin
    Using microneedling, microinjection, or cannula.

  4. Regeneration process
    The bioactive proteins immediately start repairing and rejuvenating the skin.

Duration: 30–40 minutes
Discomfort: minimal
Recovery time: none or very mild

Initial improvements appear within 7–10 days, and deeper rejuvenation continues over 4–8 weeks.

Expected results:

  • Smoother, firmer, brighter skin

  • Reduced fine lines

  • Improvement in acne scars

  • Healthier, more youthful appearance

Optimal results: 1–3 sessions depending on skin condition.

At MedYDerma, we often combine Endoret® with:

This combination accelerates healing and enhances long-term results.

  • Medical aesthetic clinic with experienced professionals

  • Certified Endoret® equipment

  • Personalized treatment protocols

  • Advanced combinations with IPL and laser

  • Natural, long-lasting results

Our goal is to help you achieve a healthier, younger-looking skin safely and effectively.

Only minimal discomfort; anesthetic cream can be applied.

Yes. It is not photosensitive.

From 7 days onward, with progressive improvement.

Between 1 and 3, depending on your goals.

Completely. It uses your own plasma.

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